Testosterone therapy
Androgens, gonadotropins, and SERMs
The base compounds of testosterone therapy — plus the fertility-preservation and hormone-restoring agents that pair with it.
Androgen · FDA-approved
Testosterone cypionate
The most-prescribed injectable testosterone ester in the United States. Weekly to twice-weekly dosing, decades of clinical use.
Androgen · FDA-approved
Testosterone enanthate
Testosterone cypionate's close chemical cousin — nearly identical pharmacokinetics, available as Xyosted (SubQ auto-injector) and Delatestryl.
Gonadotropin · Fertility
Human chorionic gonadotropin (hCG)
Preserves testicular function and fertility during testosterone therapy. Regulatory landscape shifted after the 2020 FDA biologics reclassification.
SERM · Off-label
Enclomiphene
An oral selective estrogen receptor modulator that raises endogenous testosterone. Denied FDA approval in 2015; still compounded off-label.
Growth hormone axis
GH secretagogues and growth factors
Peptides that stimulate the body's own growth hormone release — plus IGF-1 LR3, the anabolic downstream signal.
GH secretagogue
Sermorelin
A 29-amino-acid GHRH analog. Modest 1990s pediatric evidence base; widely compounded for adult off-label use with limited modern trials.
GH secretagogue combination
Ipamorelin + CJC-1295
A ghrelin-receptor agonist paired with a longer-acting GHRH analog. Frequently combined in clinical practice; no dedicated trial of the combination.
FDA-approved · GH secretagogue
Tesamorelin
The only GHRH analog with FDA approval (Egrifta / Egrifta SV) — for HIV-associated lipodystrophy. Real Phase 3 trials support the label.
Growth factor · No human trials
IGF-1 LR3
A modified insulin-like growth factor. Zero published human trials, WADA-prohibited. Distinct from FDA-approved mecasermin.
Regenerative and cosmetic peptides
Recovery, tissue repair, and cosmetic use
Peptides marketed for musculoskeletal recovery, tissue repair, and skin/hair effects — with varying regulatory status and highly variable evidence quality.
Regenerative peptide
BPC-157
A synthetic pentadecapeptide isolated from human gastric juice. Robust animal literature, ~30 total human subjects in published pilots.
Regenerative peptide · Research chemical
TB-500
A synthetic fragment of thymosin beta-4. Animal and veterinary evidence base; effectively zero human clinical trials. WADA-prohibited.
Copper tripeptide
GHK-Cu
Strong topical/cosmetic evidence; thin systemic and injectable evidence. Injectable status separated from topical in the FDA 503A list.
Metabolic cofactors
Cofactors and antioxidants
Coenzymes and antioxidant molecules used in longevity practice — where the strongest human evidence is usually for the oral precursor form, not the IV/injectable form.
Coenzyme · IV / SubQ
NAD+ (IV/SubQ)
A central metabolic coenzyme. Strongest human evidence exists for oral NR/NMN precursors — not for the IV/SubQ form Aurafil dispenses.
Antioxidant · IV / SubQ
Glutathione
The body's master antioxidant tripeptide. Oral RCT evidence exists; IV/SubQ human data is thin and documented safety concerns exist.
Nootropic peptides
Nootropic and anxiolytic peptides
Russian-developed intranasal peptides. Approved for clinical use in Russia; not FDA-approved in the United States. Evidence base is largely Russian-language.
Nootropic peptide · Russia-approved
Semax
A synthetic ACTH(4-10) analog. Approved in Russia (1998) for ischemic stroke and cognitive indications. Not FDA-approved.
Anxiolytic peptide · Russia-approved
Selank
A synthetic tuftsin analog. Approved in Russia (2009) for generalized anxiety; OTC since 2017 in Russia. Not FDA-approved.
About this library. This library exists to help patients, prospective patients, and curious readers understand the compounds discussed in modern longevity and men's health medicine. Entries are physician-reviewed and cite peer-reviewed sources, FDA documents, and regulatory notices. Some entries cover compounds Aurafil physicians may prescribe following clinical evaluation; others cover compounds Aurafil does not currently dispense and are provided for educational reference only. This library is not medical advice and does not create a doctor-patient relationship. Always consult a licensed healthcare provider before starting or changing any therapy.